Editorial: Inflammatory muscle diseases: an update

Inflammatory Markers in Infectious Diseases – an Update

A host of acute phase proteins whose concentrations increase in blood following infection or inflammations are called inflammatory markers. Hundreds of such markers have been identifiedin various infection diseases, but only very few are being measured by clinical laboratories for diagnostic purpose. While established assays for inflammatory markers like hsCRP, Immunoglobins, procalcitonin, TNF...

Mesenchymal stem cells in osteoarticular diseases: an update

Multipotent mesenchymal stromal cells or mesenchymal stem cells (MSCs) are mainly isolated from bone marrow or fat tissue. Because of their potential of multilineage differentiation towards bone, cartilage and fat tissue, they were initially evaluated to develop innovative strategies for tissue engineering applications. More recently, they have gained interest based on their immunomodulatory pr...

Inflammatory muscle diseases.

Inflammatory myopathies are the largest group of potentially treatable myopathies in children and adults. They constitute a heterogeneous group of disorders that are best classified, on the basis of distinct clinicopathologic features, in four subtypes: dermatomyositis, polymyositis, necrotizing autoimmune myositis, and inclusion-body myositis (throughout this review, I use this term to refer s...

Inflammatory muscle diseases.

The three major immune-mediated inflammatory myopathies, dermatomyositis (DM), polymyositis (PM) and inclusion body myositis (IBM), each have their own distinctive clinical features, underlying pathogenetic mechanisms and patterns of muscle gene expression. In DM a complement-dependent humoral process thought to be initiated by antibodies to endothelial cells results in a microangiopathy with s...

An Update to Surgical Management of Inflammatory Bowel Diseases